X Beauty Face Skincare Multi Brand Korean, Japanese & Chinese Products XBeauty Tylenol's Impact on Glutathione and Liver Damage Yes there is good evidence that acetaminophen (the active ingredient in Tylenol) can deplete glutathione under certain conditions. But whether that matters depends on dose, duration, and individual factors. Nini Munoz , PhD. Since the administration claimed Tylenol as a cause of autism, we've seen a number of alternative and 'integrative' practitioners talking Instagram