In the REDEFINE 2 phase 3a trial involving adults with obesity and diabetes, the use of cagrilintidesemaglutide resulted in a significantly lower body weight than placebo at 68 weeks. Full trial results Larvol Delta Cagrilintide and semaglutide together drive record weight loss in global trial Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity New England Journal of Medicine
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cagrilintide phase 2 New in the August 14, 2025, issue of NEJM: Cagrilintide–Semaglutide for Overweight or Obesity (REDEFINE 1 phase 3a trial) Cagrilintide–Semaglutide for Overweight and Diabetes (REDEFINE 2 phase 3a trial)